I remember a guy trying to sell a sealed box of Shockwave Assault for Win95 for like $2k. I dunno about other places but in late 90s game stores in Moscow were simply filled with 2-6 years old EA games for really cheap prices like $1-3, so it's as common as hydrogen in universe.
I still have new and never used copies of Donkey Kong, Metroid 2, Legend of Zelda and Super Mario Land 2 for GB. I asked for those games for birthday, both my friend and uncle got them for me, so i got 2 copies of each game, one played, one never opened since. Maybe i should sell those games for $ over 9000 each ? :D
P.S. About that Biohazard's Collector Box. A friend of mine from France got it for less than 200 euro :D